In a robust decision handed down by the English Court of Appeal, Novartis has been awarded an interim injunction against Hospira to prevent sales of generic zoledronic acid in the UK despite Novartis’ patents having been declared invalid by the English High Court. The Court of Appeal judgment represents a significant victory for Novartis and other innovators. This article discusses how this decision impacts innovators and generic companies alike, as well as the practical steps that parties should consider prior to the launch of a generic product.